GENERAL
VIROLOGY
Prince AM, Brotman B, Richard L,
White T, Pollack N, Riddle J.
Incidence of hepatitis A virus (HAV) infection in rural Liberia. J
Med Virol
15: 421-428, 1985. [205]
Williams B, Prince AM, Huima T, Brotman
B. Spuma viruses isolated from
sources containing agents of non-A, non-B hepatitis (NANB) do not cause NANB
hepatitis. J Med Virol 24: 263-274, 1988.
[229]
Marx PA, Yen L, Lerche
NW, Sutjipto S, Gettie A, Yee JA, Brotman BH, Prince AM, Hanson A, Webster RG,
Desrosiers RC. Isolation of a
simian immunodeficiency virus related to human immunodeficiency virus type 2
from a West African sooty mangabey. J Virol 65(8):
4480-4485, 1991. [266]
HEPATITIS B
VIRUS
Prince AM. Hepatitis associated antigen: Long term
persistence in chimpanzees. In ÒMedical PrimatologyÓ (1970) Basel: Karger, pp.
731, 1971. [38]
Prince AM. Immunologic distinction between I.H.
and S.H. Editorial. N Engl J
Med
281: 163-164, 1969. [41]
Prince AM, Hargrove RL, Szmuness
W, Cherubin CE, Fontana VJ, Jefferies GH.
Immunologic distinction between infectious and serum hepatitis. N
Engl J Med
282: 987-991, 1970. [42]
Vnek J, Prince AM, Hashimoto N, Ikram
H. Association of normal serum
protein antigens with chimpanzee hepatitis B surface antigen particles. J
Med Virol
2:319-333, 1978. [137]
Krawczynski K, Prince
AM,
Nowoslawski A. Immunopathologic
aspects of the HBsAg carrier state in chimpanzees. J Med Primatol 8:222-232, 1979. [150]
Prince AM, White T, Pollock N,
Riddle J, Brotman B, Richardson L.
The epidemiology of hepatitis B infections in Liberian infants. Infection
and Immunity,
May 32:675-680, 1981. [156]
Stephan W, Prince AM, Brotman B. Modulation of hepatitis B infection by intravenous application of an immunoglobulin preparation that contains antibodies to hepatitis B and core antigens but not to hepatitis B surface antigen. J Virol 51:420-424, 1984. [189]
Brotman B, Prince AM. Occurrence of Ausab test positivity
unrelated to prior exposure to hepatitis B virus. J Infect Dis 50:714-720, 1984. [192]
Berthelot P, Courouce
AM, Eyquem A, Feldmann G, Jacob J, Ravisse P, Vacher B, Moor-Jankowski J,
Muchmore E, Prince AM. Hepatitis B
vaccine safety monitoring in the chimpanzee: Interpretation of results. J
Med Primatol
13:119-133, 1984. [194]
Neurath AR, Kent SBH,
Parker K, Prince AM, Strick N, Brotman B, Sproul P. Antibodies to a synthetic peptide form the PreS 120-145
region of the hepatitis B virus envelope are virus-neutralizing. Vaccine 4:35-37, 1986. [214]
Takahashi K, Brotman B, Usuda S, Mishiro S, Prince
AM. Full-genome sequence analyses of
hepatitis B virus (HBV) strains recovered from chimpanzees infected in the
wild: implications for an origin of HBV. Virology 267: 58-64, 1999. [335]
Prince AM, Lee D-H, Brotman B. Infectivity of blood from PCR-positive,
HBsAg-negative, anti-HBs-positive cases of resolved hepatitis B infection. Transfusion 41: 329-332, 2001.
[340]
Pancholi P, Lee D-H, Liu Q, Tackney C, Taylor P,
Perkus M, Andrus L, Brotman B, Prince AM.
Immunotherapy of chronic hepatitis B virus infection. Proceedings of the 10th
International Symposium on Viral Hepatitis and Liver Disease, International Medical
Press Ltd., Atlanta, GA, pp. 196-199, 2002. [349]
Ganem D, Prince AM. Hepatitis B virus infection --- natural
history and clinical consequences.
NEJM
350(11):1118-1129, 2004. [354]
HEPATITIS B
VACCINE
Prince AM, Vnek J. A new candidate hepatitis B vaccine
containing sub particulate HBsAg and HBeAg. In Touraine J.L. et al., (Eds.):
ÒTransplantation and Clinical Immunology,Ó Amsterdam: Excerpta Medical
10:90-97, 1979. [142]
Prince AM, Vnek J. A new candidate hepatitis B vaccine
containing sub particulate HBsAg and HBeAg. In E.S. Ketiladze (Eds.): ÒViral
Hepatitis A and B. Collection of
Papers,Ó Moscow: The D.I. [143]
Prince AM, Brotman B, van den
Ende MC. Evaluation of safety and
efficacy of bivalent NIH vaccine in chimpanzees. Proceedings of the
International Workshop on Hepatitis B Vaccine, Paris, December 1980. Amsterdam:
Elsevier/North-Holland Biomedical Press. [158]
Prince AM, Vnek J, Stephan W. A new hepatitis B vaccine containing HBeAg in
addition to HBsAg. Devel Biol Stand 54:13-22, 1983. [175]
Vnek J, Hashimoto N, Prince
AM. Immunogenicity of HBeAg in New York
Blood Center Hepatitis B vaccine. Devel Biol Stand 54:217-221, 1983. [176]
Kaufmann R, Mondorf AW, Uthemann H, Bauer H, Prince AM. Hepatitis B vaccine: Safety
and efficacy clinical trial. Devel Biol Stand 54:223-228, 1983. [177]
Kaufmann R, Mondorf AW, Uthemann H, Bauer H, Prince AM. Hepatitis B vaccine:
Safety study in anti-HBs seronegative human volunteers. Devel Biol Stand 54:229-235, 1983. [178]
Prince AM, Brotman B, Purcell RH,
Gerin JL. Infection with hepatitis
B virus after successful immunization with hepatitis B virus vaccine: A final report on safety and immunogenicity
of a bivalent aqueous subunit vaccine.
J Med Virol
15:399-419, 1985. [196]
Prince AM, Vnek J, Brotman
B. An affordable multideterminant
plasma derived hepatitis B virus vaccine. Proc. Symposium on Virus-Associated
Cancers in Africa, Nairobi, IARC Scientific Publications No. 63:355-372, 1984. [200]
Lelie PN, Reesink HW,
Niessen J, Brotman B, Prince AM.
Inactivation of 1015 chimpanzee-infectious doses of hepatitis
B virus during preparation of a heat-inactivated hepatitis B vaccine. J Med
Virol 23:289-295,
1987. [232]
Shata MT, Brotman B,
Perkus M, Lee D-H, Li L, Tricoche N, Murthy K, Prince AM. Attempted therapeutic immunization in a
chimpanzee (Pan troglodytes) chronic HBV carrier with a high viral
load. J Med Primatol. 35:165-171, 2006
VIRUS-FREE
BLOOD DERIVATIVES
Stephan W, Prince AM, Brotman B, van den
Ende MC. Wirksamkeitsnachweis der sterilisation humaner
gerinnungsfaktoren mit β-propiolactone und UV-bestrahlung. In Deutsch, E, Lechner K. (Eds.):
ÒFibrinolyse, Thrombose, HŠmostase,Ó Schattauer Verlag Stuttgart, pp. 589-592,
1980. [152]
Stephan W, Prince AM. Efficacy of combined treatment of
factor IX-complex (PPSB) with β-propiolactone (β-PL) and ultraviolet
(UV) irradiation. Protides of Biological Fluids. 28:229-232, 1980.
[153]
Prince AM, Stephan W, Brotman B,
van den Ende MC. Evaluation of the
effect of beta-propiolactone/ultraviolet irradiation (β-PL/UV) treatment
of source plasma on hepatitis transmission by factor IX complex in
chimpanzees. Thrombosis and
Haemostasis
44:138-142, 1980. [155]
Prince AM, Stephan W. Effect of combined
β-propiolactone/ultraviolet irradiation treatment on hepatitis B virus.
Letter to the Editor, Lancet ii: 917, 1980. [157]
Stephan W, Berthold H, Prince
AM. Effect of combined treatment of serum
containing hepatitis B virus with beta-propiolactone and ultraviolet
irradiation. Vox Sang 41:134-138, 1981. [161]
Stephan W, Kotitschke R,
Prince AM,
Brotman B. Long-term tolerance and
recovery of β-propiolactone/ultraviolet (βPL/UV) treated PPSB in
chimpanzees. Thrombosis and Haemostasis 46:511-514, 1981. [162]
Prince AM, Stephan W, Brotman
B. Efficacy of combined treatment
of human plasma with β-propiolactone and UV irradiation. Blutkomponenten und Plasmaersatzmittel. J.R. Kalden and U.D. Koenig (Eds.)
Springer-Verlag, Berlin, Heidelberg, New York, 1982, pp. 68-86. [172]
Kotitschke R, Stephan W, Prince AM. Thrombogenitatstestergebnisse von
kalsterilisiertem PPSB am Schimpansen. Blutkomponenten und Plasmaersatzmittle.
J.R. Kalden and U.D. Koenig (eds.), Springer-Verlag, Berlin, Heidelberg, New
York, 1982, pp. 107-112. [173]
Prince AM, Horowitz B, Brotman B, Huima T,
Richardson L, van den Ende MC. Inactivation of
hepatitis B and Hutchinson strain non-A, non-B hepatitis viruses by exposure to
Tween 80 and ether. Vox Sang 46:36-43, 1984. [185]
Prince AM, Stephan W, Brotman
B. Inactivation of non-A, non-B
virus infectivity by a beta-propiolactone/ultraviolet irradiation treatment and
aerosil adsorption procedure used for preparation of a stabilized human serum. Vox
Sang
46:80-85, 1984. [186]
Prince AM, Stephan W, Kotitschke
R, Brotman B. Inactivation of
hepatitis and non-A, non-B viruses by combined use of Tween 80,
β-propiolactone, and ultraviolet irradiation. Thrombosis and
Haemostasis 50:534-536,
1983. [201]
Prince AM, Stephan W, Kotitschke
R, Brotman B. Inactivation of the
Hutchinson strain non-A, non-B hepatitis virus by combined use of
β-propiolactone and ultraviolet irradiation. J Med Virol 16:119-125, 1985. [203]
Prince AM, Horowitz B,
Dichtelmueller H, Stephan W, Gallo RC. Quantitative assays for evaluation of
HTLV-III inactivation procedures: tri (N-butyl) phosphate/sodium cholate and
β-propiolactone. Cancer Research 45:4592s-4592s, 1985. [206]
Einarsson M, Prince
AM,
Brotman B. Removal of non-A, non-B
hepatitis-virus from a concentrate of the coagulation factor-II, factor-VII,
factor-IX and factor-X by hydrophobic interaction chromatography. Scand J
Infec Dis
17:141-146, 1985. [207]
Prince AM, Horowitz B, Brotman
B. Inactivation of viruses in
labile blood derivatives 3. Sterilization of hepatitis and HTLV-III viruses by
exposure to tri (N-Butyl) phosphate and sodium cholate. Lancet i:706-710, 1986.
[212]
Prince AM. Effect of heat treatment
of lyophilized blood derivatives on infectivity of human immunodeficiency
virus. Lancet
i: 1280, 1986. [215]
Prince AM, Horowitz B, Horowitz
MS, Zang E. The development of
virus-free labile blood derivatives - a review. Eur J Epidemiol 3:103-118, 1987. [222]
Stephan W, Dichtelmuller
H, Prince AM,
Brotman B, Huima T. Inactivation
of the Hutchinson strain of hepatitis non-A, non-B virus in intravenous
immunoglobulin by β-propiolactone. J Med Virol 26:227-232, 1988. [238]
Horowitz B, Prince AM. Laboratory and preclinical evaluation
of the virus safety of coagulation factor concentrates. Develop Biol
Standard 67:291-302,
1987. [244]
Horowitz B, Williams B,
Rywkin S, Prince AM, Pascual D, Geacintov N, Valinsky J. Inactivation of viruses in blood with
aluminum phthalocyanine derivatives.
Transfusion 31(2): 102-108, 1991. [263]
Horowitz B, Bonomo R, Prince
AM,
Chin SN, Brotman B, Shulman RW.
Solvent/detergent-treated plasma: A virus-inactivated substitute for
fresh frozen plasma. Blood 79:826-831, 1992. [287]
Gao F, Prince AM, Pascual D, Horowitz
B. Enhancement in the safety of
immune globulins prepared from high-risk plasma. Vox Sang 64:204-209, 1993. [290]
Horowitz B, Prince AM, Hamman J, Watklevicz,
C. Viral safety of
solvent/detergent treated blood products. Blood Coagulation and Fibrinolysis 5:S21-S28, 1994. [295]
Prince AM, Horowitz B. Virus safety of pooled fresh-frozen
plasma inactivated by solvent/detergent treatment. Transfusionsmedizin 31: 21-24, 1993. [304]
Lavie G, Mazur Y, Lavie
D, Prince AM,
Pascual D, Liebes L, Levin B, Meruelo D.
Hypericin as an inactivator of infectious viruses in blood products. Transfusion 35:392-400, 1995. [311]
Prince AM, Horowitz B. Viral safety of solvent/detergent
treated intravenous immune globulin. -Letter to the Editor, NEJM 332:1236, 1995. [312]
Prince AM, Pascual D, Meruelo D,
Liebes L, Mazur Y, Dubovi E, Mandel M, Lavie G. Strategies for evaluation of
enveloped virus inactivation in red cell concentrates using hypericin. Photochemistry
and Photobiology
71(2): 188-195, 2000. [336]
Prince AM. Hepatitis viruses and blood
transfusion. Blood Safety and Surveillance, Linden JV and Bianco C (Eds): Marcel
Dekker, Inc., Ch. 12, pp. 279-293, 2001. [338]
CHIMPANZEE
STUDIES
Prince AM. Infection of chimpanzees with hepatitis
B virus. In Vyas, G.N., Perkins, H.A., Schmid R., editors: Hepatitis and
Blood Transfusion,
New York: Grune & Stratton, pp. 403-406, 1972. [173]
Prince AM. Use of chimpanzees as a model for the
study of hepatitis B virus infections. Med Primatol 3:97-109, 1972. [74]
Trepo C, Prince AM. Attempted immunotherapy with dialyzable
transfer in hepatitis B carrier chimpanzees: Induction of delayed
hypersensitivity to hepatitis B surface antigen (HBsAg). In Asher, M. (Ed.): Transfer Factor. New York: Academic Press, pp. 449-456,
1976. [118]
Prince AM, Vnek J, Brotman B, Hashimoto N, van
den Ende MC. Comparative evaluations
of hepatitis B vaccines in chimpanzees and in man. In Vyas G.N., Cohn S.N,
Schmid R. (Eds.): Viral Hepatitis, Philadelphia: Franklin Inst. Press, pp.
507-523, 1978. [138]
Prince AM, Brotman B, van den
Ende MC, Richardson L. Non-A,
non-B hepatitis: Reproduction of disease in chimpanzees and identification of
virus specific antigen and antibody.
In Touraine JL, et al., (Eds.): Transplantation and Clinical
Immunology,
Amsterdam: Excerpta Medica 10:8-17, 1979. [140]
Van den Ende MC, Brotman
B, Prince AM. ÒAn open air holding system for
chimpanzees in medical experiments.Ó Develop. Biol. Standard. Basel: S. Karger
45:95-98, 1980. [148]
Prince AM. ÒThe use of chimpanzees in biomedical
research.Ó Trends in Bioassay Methodology: In vivo, In vitro and
Mathematical Approaches, US Government Printing Office, 1981, pp. 81-97. [160]
Prince AM. Reliability of chimpanzee model for
non-A, non-B hepatitis. Lancet ii: 1134, 1985. [208]
Prince AM, Brotman B, Hannah A,
Donnelly M, Hentschel K, Roth H.
Rehabilitation and release to the wild of chimpanzees used in medical
research. SSC/UUCN Primate Specialist Group, 1986. [218]
Lenz G, Junger H,
Schneider M, Kothe N, Lissner R, Prince AM.
Elimination of pyridoxylated polyhemoglobulin after partial exchange
transfusion in chimpanzees. Biomat Art Cells &
Immob Biotech 19(4): 699-708, 1991. [276]
Lenz G, Junger H, van den Ende R, Brotman B, Prince AM. Hemodynamic effects
after partial exchange transfusion with pyridoxylated polyhemoglobin in
chimpanzees. Biomat Art Cells & Immob Biotech 19(4): 709-718, 1991. [277]
Abe K, InchauspŽ G, Shikata T, Prince AM. Three different patterns of hepatitis C virus
infection in chimpanzees. Hepatology 15:690-695, 1992. [285]
Luder CGK, Soboslay PT, Prince
AM,
Greene BM, Lucius R, Schultz-Key H.
Experimental onchocerciasis in chimpanzees: cellular responses and
antigen recognition after immunization and challenge with Onchocerca
volvulus
infective third-stage larvae. Parasitology 107:87-97, 1993. [302]
Prince AM, Whalen R, Taylor P,
Brotman B. Protective efficacy of
DNA-based immunization against HBV in newborn chimpanzees. Vaccines 97. Cold Spring Harbor
Laboratory 141-144. [322]
Prince AM, Whalen R, Brotman
B. Successful nucleic acid based
immunization of newborn chimpanzees against hepatitis B virus. Vaccine 15: 916-919, 1997.
[327a]
Prince AM, Brotman B. Biological and immunological aspects of hepatitis C virus infection in chimpanzees. Curr Stud Hematol Blood Transf 62:250-265, 1998. [324]